The classic 5 by 8 ft bathroom fits a tub, toilet and vanity in a row, because each fixture just clears its code minimums: 15 inches beside the toilet, 21 inches in front. Below that size you trade: a 6 by 6 wants a shower instead of a tub, and a powder room works down to about 30 by 60 inches. The decider is never floor area, it is clearances.

Sketch your exact room in the free bathroom planner, in feet and inches or centimeters: the code check and comfort guidelines run live, the door swing is drawn on the plan, and moving a fixture shows its plumbing cost immediately.
Around 5 by 7 ft with a shower instead of a tub, if the door swings out or slides. It passes clearances, but nothing is generous; draw it in the planner before you commit, because a few inches of wall move can be the difference.
Outward or sliding wins in tight rooms: an inward swing eats the exact strip of floor the clearances need. The planner draws the door swing on the floor plan so the conflict is visible instead of theoretical.
Often yes, and that is where budgets are won or lost: shifting a toilet along the wet wall is modest, crossing the room is not. The cost guides on this site give ranges, and the planner calculates your exact distances.